【摘要】

目的 观察对更年期抑郁症女性患者采用心身并治的临床疗效及对其抑郁程度和激素水平的影响。
方法 选取2018年5月～2019男5月期间本院收治的120例更年期抑郁症女性患者作为研究对象。随机分组，比较A组（盐酸舍曲林治疗，n=40）、B组（盐酸舍曲林+加味二仙汤，n=40）和C组（心身并治，n=40）的临床疗效。
结果 三组临床疗效及生活质量评分比较具显著性差异（P<0.05）。三组治疗后SDS评分相比治疗前均明显降低（P<0.05），但三组比较无显著性差异（P>0.05）；三组雌二醇 (E2 )水平相比治疗前无明显变化（P>0.05）；B组、C组卵泡刺激素 (FSH)水平有显著下降（P<0.05），C组促黄体生成素（LH）水平有显著下降（P<0.05），三组比较无显著性差异（P>0.05）。
结论 对更年期抑郁症女性患者采用心身并治可有效缓解患者抑郁程度，降低FSH和LH水平，改善患者抑郁状态。

【Abstract】

Objective To observe the clinical effect of psychosomatic therapy on female patients with menopausal depression and its effect on depression degree and hormone level.
Methods 120 female patients with menopausal depression who were admitted to our hospital from May 2018 to May 2019 were selected as the study subjects. Randomized grouping, compared the clinical efficacy of group A (sertraline hydrochloride treatment, n=40), group B (sertraline hydrochloride + modified Erxian decoction, n=40) and group C (psychosomatic treatment, n=40).
Results There were significant differences in clinical efficacy and quality of life scores among the three groups (P<0.05). The SDS scores of three groups after treatment were significantly lower than those before treatment (P< 0.05), but there was no significant difference among the three groups (P>0.05); the level of estradiol (E2) in three groups had no significant change (P>0.05); the level of follicle stimulating hormone (FSH) in group B and C had significant decrease (P<0.05), and the level of luteinizing hormone (LH) in group C had significant difference. There was no significant difference among the three groups (P>0.05).
Conclusion   Psychosomatic therapy can effectively relieve depression, reduce the levels of FSH and LH, and improve depression in female patients with menopausal depression.