本刊首页 > 期刊目次 > 团体心理治疗辅助奥氮平治疗精神分裂症患者临床疗效及对社会功能的影响

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团体心理治疗辅助奥氮平治疗精神分裂症患者临床疗效及对社会功能的影响

  • 刘海平

* 通信作者: 刘海平, 单位:粤北第三人民医院

摘要


目的:研究团体心理治疗辅助奥氮平治疗精神分裂症患者临床疗效及对社会功能的影响。

方法:选取2016年5月-2017年7月我院收治的106例精神分裂患者为研究对象,按照随机数表法将所选患者分为对照组与观察组;对照组患者口服奥氮平治疗,观察组在对照组的基础上辅以团体心理治疗,比较两组治疗前后社会功能改善情况以及临床疗效,并观察两组安全性。

结果:①治疗前两组PSP评分无明显差异(P>0.05),治疗后两组PSP评分有明显差异,观察组评分明显高于对照组(F=627.55,P<0.001),治疗后各时间点两组PSP评分均存在明显差异(F=153.27,P<0.001);治疗后两组PSP评分随时间变化而存在差异(F=53.27,P<0.001);②治疗前两组PANSS评分无明显差异(P>0.05),治疗后两组PANSS评分有明显差异,观察组评分明显低于对照组(F=532.17,P<0.001),治疗后各时间点两组PANSS评分均存在明显差异(F=127.35,P<0.001);治疗后两组PANSS评分随时间变化而存在差异(F=46.35,P<0.001);③观察组总有效率为94.34%明显高于对照组的79.25%,差异具有统计学意义(P<0.05);④对照组不良反应发生率为5.66%;观察组不良反应发生率为9.43%;两组比较,差异无统计学意义(2=0.541,P=0.462)。

结论:运用奥氮平治疗精神分裂患者的过程中辅以团体心理治疗,可有效的改善患者的社会功能,提高临床治疗效果。

关键词:奥氮平;团体心理治疗;社会功能;临床疗效;精神分裂

ABSTRACT

To investigate the clinical efficacy of group psychotherapy assisted with olanzapine in the treatment of patients with schizophrenic and its effect on social function.

Methods: 106 cases with Schizophrenia in our hospital from May 2016 to July 2017 were selected as the research object. The cases were randomly divided into control group and observation group. The cases in the control group were treated with olanzapine, and the cases in the observation group were given with group psychological treatment on the bases of the treatment of the control group. The social function improvement before and after treatment and the clinical efficacy and safety were observed and compared in the two groups.

Results: (1)The PSP score of two groups before treatment had no significant difference (P>0.05). After treatment, the PSP score had significant difference between two groups, and the PSP score of observation group were significantly higher than that of the control group (F=627.55, P<0.001). The PSP scores of the two groups were significantly different at each time point after treatment(F=153.27, P<0.001). After treatment, the PSP score of two groups changed with the development of time (F=53.27, P<0.001). (2)before treatment, the PANSS score of two groups had no significant difference (P>0.05). After treatment, the PANSS score of two groups had significant difference, and the PANSS score of observation group was significantly lower than that in the control group (F=532.17, P<0.001). The PANSS scores of the two groups were significantly different at each time point after treatment(F=127.35, P<0.001). The PANSS score of two groups changed with the development of time (F=46.35, P<0.001); (3)the total efficiency of the observation group was 94.34%, which was significantly higher than that in the control group (79.25%) with statistical difference Significance (P<0.05). (4)the incidence of adverse reactions in the control group was 5.66% and the incidence of adverse reactions in the observation group was 9.43%; there was no significant difference about the adverse reactions between the two groups (χ2=0.541, P=0.462).

Conclusion  : The application of group psychotherapy in the treatment of schizophrenic patients with olanzapine can effectively improve the social function of the patients, and improve the clinical effect.

Key words: Olanzapine; Group psychotherapy; Social function; Clinical efficacy; Schizophrenia.

引用本文 / How to Cite This Article

刘海平.团体心理治疗辅助奥氮平治疗精神分裂症患者临床疗效及对社会功能的影响[J]. 国际精神病学杂志, 2019, 46(5): 846-849

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