【摘要】

【摘要】目的 了解维、汉、哈族慢性康复期精神分裂症患者事件相关电位（ ＥＲＰ ）检查
结果的差异。
方法 对符合入组标准的2018年6月至2019年6月在我院住院治疗的慢性康复期精神分裂症患者维族30例（观察1组），哈族30例（观察2组）及汉族患者200例（对照组）进行事件相关电位检查，比较三组患者MMN、P300相关靶点检测指标。
结果 三组患者的Fz、Cz 、Pz三个电极 MMN 、P300 的潜伏期均显示延迟，波幅降低。观察1组 Fz、Cz 、Pz三个电极 MMN 、P300 的潜伏期延迟及波幅降低程度均小于对照组。观察2组Fz、Cz 、Pz三个电极 MMN 、P300 的潜伏期延迟及波幅降低程度均小于对照组。观察1组和2组Fz、Cz 、Pz三个电极 MMN 、P300 的潜伏期延迟及波幅降低程度相比较无明显差异。三组患者P50比值均显示增大，组间比较无明显差异。
结论 比较三组患者的ERP发现汉族精神分裂症患者MMN及P300的认知电位潜伏期延迟较维族哈族患者显著。民族差异对精神分裂症患者的认知功能可能有影响。

【Abstract】

【Abstract】Objective to investigate the difference of event-related potential (ERP) in patients with chronic convalessive schizophrenia. Method to meet the standard set of June 2018 to June 2019 in our hospital rehabilitation of chronic schizophrenia patients hospitalized with Uighur 30 cases (observed group 1), of the 30 cases 200 cases (observation group 2) and the han nationality patients (control group) for event related potential test, compare three groups of patients with MMN, P300 related targets detected by the index.
Results the latency of Fz, Cz, Pz, MMN and P300 of the three groups of patients all showed delay and decreased amplitude. The latency delay and amplitude reduction of Fz, Cz and Pz electrodes MMN and P300 in group 1 were lower than those in control group. The latency delay and amplitude reduction of Fz, Cz and Pz electrodes MMN and P300 in the 2 groups were lower than those in the control group. The latency delay and amplitude reduction of Fz, Cz and Pz electrodes MMN and P300 in group 1 and group 2 showed no significant difference. P50 ratio was increased in all three groups, but there was no significant difference between the groups.
Conclusion   compared with the three groups of patients, ERP found that the latency of cognitive potential of MMN and P300 in han patients with schizophrenia was significantly higher than that in uyghur and ha patients. Ethnic differences may have an effect on cognitive function in schizophrenia.