【摘要】

目的：探讨抑郁症合并糖耐量异常患者采用舍曲林与疏导疗法联合治疗的临床价值。
方法：选择2017年2月-2018年7月期间我院收治的104例抑郁症合并糖耐量异常患者为研究对象，根据数字随机法将其分为两组，其中对照组采用单一舍曲林治疗，而观察组在此基础上，再运用疏导疗法联合治疗，比较两组治疗效果。
结果：治疗前，两组血糖水平比较无差异（P>0.05）；治疗后，观察组的2hPG水平低于对照组（P<0.05）；与对照组比较，观察组的治疗有效率高，组间对比差异明显（P<0.05）；两组治疗前的各项评分无可比性（P>0.05）；治疗后，与对照组相比，观察组的HAMD和SDS评分均较低，组间对比有显著差异（P<0.05）；观察组的生活质量评分高于对照组（P<0.05）；但是两组的不良反应发生率比较无差异（P>0.05）。
结论：临床上运用舍曲林和疏导疗法对抑郁症合并糖耐量异常患者进行联合治疗效果显著。

【Abstract】

Objective: To explore the clinical value of sertraline combined with dredging therapy in the treatment of depression with impaired glucose tolerance.
Methods: 104 patients with depression and impaired glucose tolerance admitted to our hospital from February 2017 to July 2018 were selected as the study objects. They were divided into two groups according to the digital random method. The control group was treated with a single sertraline, while the observation group was treated with the combination of dredging therapy on the basis of this, and the treatment effect of the two groups was compared.
Results: before treatment, there was no difference in blood glucose level between the two groups (P > 0.05); after treatment, the level of 2hPG in the observation group was lower than that in the control group (P < 0.05); compared with the control group, the treatment efficiency of the observation group was higher, and the difference between the groups was significant (P < 0.05); before treatment, the scores of the two groups were not comparable (P > 0.05); after treatment, compared with the control group, the HAMD and SDS scores of the observation group were all higher The quality of life score of the observation group was higher than that of the control group (P < 0.05), but there was no difference in the incidence of adverse reactions between the two groups (P > 0.05).
Conclusion  : sertraline and dredging therapy are effective in the treatment of depression with abnormal glucose tolerance.