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心理治疗联合奥氮平对重症器质性精神障碍的治疗效果分析

  • 张慧芳

* 通信作者: 张慧芳, 单位:驻马店市第二人民医院

摘要

【摘要】
目的 研究心理治疗联合奥氮平对重症器质性精神障碍的治疗效果。

方法 选择本院2017年1月1日至2019年12月31日220例重症器质性精神障碍患者作为研究对象,按随机数字表法均分为对照组和联合组,对照组采取奥氮平治疗,联合组在对照组的基础上联合心理治疗。比较两组阳性与阴性症状评分(PANSS)、心理健康量表(SCL-90)、健康调查简表(SF-36)、不良反应。

结果 对照组治疗后的PANSS总分显著高于联合组,差异有统计学意义(P<0.05)。对照组治疗后的SCL-90显著高于联合组,SF-36显著低于联合组,差异均有统计学意义(P<0.05)。对照组不良反应率10.91%与联合组不良反应率5.45%比较,差异无统计学意义(P>0.05)。

结论 心理治疗联合奥氮平可显著降低重症器质性精神障碍患者的精神障碍程度,改善其心理与生活质量。

关键词:【关键词】心理治疗;奥氮平;器质性精神障碍;PANSS;SCL-90;SF-36

ABSTRACT

[Abstract]
Objective To study the effect of psychotherapy combined with olanzapine in the treatment of severe organic mental disorders.

Methods A total of 220 patients with severe organic mental disorder from January 1, 2017 to December 31, 2019 were selected as the study subjects. According to the random number table method, they were divided into the control group and the combined group. The control group was treated with olanzapine, and the combination group was combined with psychological treatment based on the control group. The positive and negative symptom scores (PANSS), mental health scale (SCL-90), health survey summary (SF-36), and adverse reactions between the two groups were compared.

Results The total score of PANSS after treatment in the control group was significantly higher than that in the combined group, and the difference was statistically significant (P<0.05). The SCL-90 in the control group after treatment was significantly higher than that in the combined group, and SF-36 was significantly lower than that in the combined group, and the differences were statistically significant (P<0.05). The adverse reaction rate in the control group was 10.91% and the adverse reaction rate in the combined group was 5.45%. There was no significant difference (P>0.05).

Conclusion   Psychotherapy combined with olanzapine can significantly reduce the degree of mental disorders in patients with severe organic mental disorders and improve their psychological and quality of life.

Key words: Key words Psychotherapy; Olanzapine; Organic Mental Disorder; PANSS; SCL-90; SF-36

引用本文 / How to Cite This Article

张慧芳.心理治疗联合奥氮平对重症器质性精神障碍的治疗效果分析[J]. 国际精神病学杂志, 2020, 47(4): 733-735

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