【摘要】

【摘要】 目的 分析脑胶质瘤围术期患者应用家庭干预联合丙戊酸钠注射液干预后负面情绪及应激状态改变。
方法 将我院95例脑胶质瘤围术期患者采用随机数字表法分组，对照组47例给予丙戊酸钠注射治疗，观察组48例增加家庭干预联合治疗，观察两组患者围术期不同时间段收缩压、心率水平变化，比较两组患者治疗前后焦虑、抑郁自评量表评分变化，并对比两组患者治疗后临床疗效。
结果 治疗后，观察组SDS评分、SAS评分均低于对照组，总有效率高于对照组（P<0.05）；观察组T2、T3、T4时间段收缩压及心率水平低于对照组 （P<0.05）。
结论 家庭干预联合丙戊酸钠能够有效减轻脑胶质瘤围术期患者机体应激反应，缓解焦虑抑郁负面情绪。

【Abstract】

[Abstract] Objective To analyze the changes of negative emotions and stress states in patients with glioma during perioperative period after home intervention combined with sodium valproate injection.
Methods Ninety-five patients with gliomas in our hospital were grouped by random number table method. The control group was given sodium valproate injection in 47 cases. The observation group was given 48 cases of family intervention and combined treatment. The perioperative period of the two groups was observed. The changes in systolic blood pressure and heart rate at different time periods were compared between the two groups of patients before and after treatment, and the clinical efficacy after treatment.
Results After treatment, the SDS score and SAS score of the observation group were lower than the control group, and the total effective rate was higher than the control group (P <0.05); the systolic blood pressure and heart rate of the observation group at T2, T3, and T4 were lower than the control group (P <0.05).
Conclusion   Family intervention combined with sodium valproate can effectively reduce the stress response of patients with glioma during perioperative period, and relieve the negative emotions of anxiety and depression.