关键词：[关键词] 脑卒中后抑郁 重复经颅磁刺激 P300电位 认知功能
【Abstract】 Objective To explore the efficacy of repetitive transcranial magnetic stimulation in patients with post-stroke depression .Methods 120 cases of patients with post-stroke depression were divided into drug treatment only group,drug combined with pseudo-stimulation treatment group and drug combined with repetitive transcranial magnetic stimulation group. Forty patients were in each group. P300, the Hamilton depression scale and mini-mental state examination were observed at baseline and after treatment of 2 weeks, 4 weeks and 8 weeks. Results There were significant decrease of the scores of HAMD in the drug combined with repetitive transcranial magnetic stimulation group than the other two groups(P＜0.05). The scores of MMSE in the rTMS group were statistically significant higher than others after treatment of 4 weeks(P＜0.05). There were shorter latency and increased amplitude of P300 in the rTMS combined with drug group after treatment of 8 weeks. Conclusion The repetitive transcranial magnetic stimulation combined with SSRIs can improve the depressive symptoms and cognitive function in patients with post-stroke in early stage.
Key words: Key words：Post-stroke depression,Repetitive transcranial magnetic stimulation，P300 potentials, Cognitive function
引用本文 / How to Cite This Article
余寒.重复经颅磁刺激联合SSRIs类药物对老年脑卒中后抑郁患者认知功能的临床研究[J]. 国际精神病学杂志, , (): -