【摘要】目的 研究重复经颅磁刺激(rTMS)对老年糖尿病合并认知功能障碍疗效及P300电位的影响。方法 选择本院2017年11月到2019年11月60例老年糖尿病合并认知功能障碍患者作为研究对象，按随机数字表法均分为对照组和研究组。对照组采取常规治疗，研究组在对照组的基础上采取rTMS治疗。比较两组的蒙特利尔认知功能评估量表(MoCA)、P300电位。结果 对照组治疗后的MoCA总分显著低于研究组， (P<0.05)。对照组治疗后的P300潜伏期显著高于研究组，P300波幅显著低于研究组， (P<0.05)。结论 rTMS可显著改善老年糖尿病患者的认知功能，从而延缓病情进展，促进临床疗效，可根据患者的实际情况深入研究使用。
[Abstract] Objective To study the effect of repeated transcranial magnetic stimulation (rTMS) on the efficacy and P300 potential of senile diabetes with cognitive dysfunction. Methods Sixty patients with diabetes mellitus complicated with cognitive dysfunction from November 2017 to November 2019 were selected as the study subjects. They were randomly divided into the control group and the study group according to random number table method. The control group took conventional treatment, and the study group took rTMS treatment based on the control group. The Montreal Cognitive Function Assessment Scale (MoCA) and P300 potential between the two groups were compared. Results The total MoCA score of the control group after treatment was significantly lower than that of the study group, (P<0.05). The P300 incubation period of the control group after treatment was significantly higher than that of the study group, and the amplitude of P300 was significantly lower than that of the study group, (P<0.05). Conclusion rTMS can significantly improve the cognitive function of elderly diabetic patients, thereby delaying the progression of the disease and promoting clinical efficacy. It can be used in-depth research according to the actual situation of patients.
引用本文 / How to Cite This Article
李晖.重复经颅磁刺激对老年糖尿病合并认知功能障碍疗效及P300电位的影响[J]. 国际精神病学杂志, 2021, 48(2): 298-300