【摘要】 目的 分析突发性聋伴焦虑患者应用氯硝西泮辅助治疗后疗效及对睡眠质量与不良情绪的影响。方法 采用随机数字表法将我院91例突发性聋伴焦虑患者进行分组，两组患者均给予糖皮质激素、抗凝、营养神经等基础治疗，对照组45例给予心理干预，观察组46例在对照组基础上增加氯硝西泮联合治疗，对比两组患者治疗后焦虑抑郁情绪变化，睡眠质量、临床疗效及治疗期间不良反应发生率。结果 治疗7、14d后，观察组HAMA、PSQI、HAMD评分均低于对照组（P<0.05）；治疗后，观察组总有效率高于对照组（P<0.05）；两组患者不良反应发生率无统计学意义（P>0.05）。结论 氯硝西泮辅助治疗能够有效改善突发性聋伴焦虑患者不良情绪，提升睡眠质量及治疗效果，安全有效。
【Abstract】 Objective To analyze the effect of adjuvant clonazepam on patients with sudden deafness and anxiety and the effect on sleep quality and bad mood. Methods A random number table method was used to group 91 patients with sudden deafness and anxiety in our hospital. Patients in both groups were given basic therapy such as glucocorticoids, anticoagulation, and nutritional nerves. 45 patients in the control group were given psychological intervention. The observation group 46 Cases added clonazepam combination therapy on the basis of the control group, comparing the changes of anxiety and depression mood, sleep quality, clinical efficacy and incidence of adverse reactions during treatment between the two groups of patients. Results After 7 and 14 days of treatment, the HAMA, PSQI, and HAMD scores of the observation group were lower than those of the control group (P<0.05); after treatment, the total effective rate of the observation group was higher than that of the control group (P<0.05); adverse reactions occurred in two groups of patients The rate was not statistically significant (P>0.05). Conclusion Clonazepam adjuvant therapy can effectively improve the unhealthy mood of patients with sudden deafness and anxiety, improve sleep quality and treatment effect, and is safe and effective.
引用本文 / How to Cite This Article
张卫杰.氯硝西泮辅助治疗突发性聋伴焦虑患者的效果及对焦虑抑郁情绪与睡眠质量的影响[J]. 国际精神病学杂志, 2021, 48(2): 323-325