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长期住院精神分裂症患者认知功能5年随访及与阴性症状相关分析

  • 闫妍,陶一之,刘家宾,汪晓晖

* 通信作者: 汪晓晖, 单位:上海市青浦区精神卫生中心 201700

摘要

【摘要】
目的 了解男性长期住院精神分裂症患者5年随访认知功能变化及阴性症状对其影响。

方法 选取精神分裂症男性患者160名,采用重复性成套神经心理状态测验(RBANS)及阳性和阴性症状量表(PANSS)对患者5年前及5年后进行测评。使用SPSS17.0进行统计学分析。

结果:语言功能、视觉广度五年后比五年前评分降低,阴性症状、一般精神病理五年后比五年前升高(p≤0.05);阴性症状、一般精神病理与RBANS量表各因子分呈负相关关系(p≤0.05);阴性症状对语言功能及视觉广度有预测效应(p≤0.05),可分别解释语言功能及视觉广度方差变异的23.7%及19.2%。

结论 :长期住院精神分裂症患者五年后认知功能减退,阴性症状、一般精神病理加重,阴性症状是语言功能及视觉广度的预测因子。

关键词:【关键字】 精神分裂症;认知功能;阴性症状;相关因素;

ABSTRACT

【Abstract】
Objective:To understand the changes in cognitive function of male long-term hospitalized patients with schizophrenia and the influence of negative symptoms on it.

Methods:A total of 168 male patients with schizophrenia were selected. The Repetitive Neuropsychological State Test (RBANS) and the Positive and Negative Symptom Scale (PANSS) were used to evaluate the patients 5 years ago and 5 years later. Statistical analysis was performed using SPSS17.0.

Results: The scores of language function and vision span decreased after five years compared with five years ago, and negative symptoms and general psychotic symptoms increased after five years than five years ago (p≤0.05); negative symptoms, general psychotic symptoms and RBANS scale The scores of each factor are negatively correlated (p≤0.05); negative symptoms have a predictive effect on language function and visual span (p≤0.05), which can explain 23.7% and 19.2% of the variance of language function and visual span, respectively.

Conclusion  : The patient's language function and vision span decreased after five years, and negative symptoms and general psychotic symptoms worsened after five years. Negative symptoms and general psychotic symptoms were related to cognitive function. Negative symptoms were predictors of language function and vision span.

Key words: [Keywords] schizophrenia; cognitive function; negative symptoms; related factors;

引用本文 / How to Cite This Article

闫妍,陶一之,刘家宾,汪晓晖.长期住院精神分裂症患者认知功能5年随访及与阴性症状相关分析[J]. 国际精神病学杂志, , (): -

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