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综合医院心身门诊重性抑郁症患者生活质量和影响因素分析

  • 郑晓静,王传跃,周福春

* 通信作者: 王传跃, 单位:首都医科大学附属北京安定医院

摘要

【摘 要】
目的:评估重性抑郁障碍患者生活质量,分析其相关因素,提示干预措施。

方法:对符合美国精神障碍诊断与统计手册DSM-Ⅳ诊断的137例重性抑郁障碍患者,使用世界卫生组织生存质量测定量表简表(WHOQOL-BREF、HAMD抑郁量表、HAMA焦虑量表、患者健康调查问卷(PHQ-9)、Sheehan残疾量表(SDS)、DSM-Ⅳ-TR轴Ⅰ障碍定式临床检查工具进行评估。

结果:患者WHOQOL-BREF生理领域[(10.86±1.73) vs (12.13±1.99)],心理领域[(10.79±1.62)vs (12.61±1.97)],社会关系领域[(11.18±2.77)vs (13.45±2.79)],环境领域[(12.50±2.13)vs (13.84±2.24)],得分均低于国内常模(P<0.01),并与HAMD总分,PHQ-9总分,SDS工作总分相关,回归分析显示患者生活质量总分与PHQ-9分,SDS工作分,婚姻,病史呈负相关。

结论:①抑郁症患者生活质量较差;②患者抑郁程度越重,病史越长,功能缺损越严重,生活质量越差,另外年龄,性别,共病,饮酒,病史也影响患者的生活质量的不同方面。针对相关因素进行干预,有助于提高患者的生活质量。

关键词:【关键词】 抑郁障碍,生活质量,相关因素

ABSTRACT

Abstract)
Objective:To explore the quality of life and related factors in major depression disorder.

Methods: Totally 137 patients of major depression disorder according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-Ⅳ) were selected. The World Health Organization Quality of Life-Brief Version (WHOQOL-BREF), HAMD, HAMA, PHQ-9, Sheehan (SDS) and Structured Clinical Interview for DSM- Ⅳ axis-Ⅰ disorders were administered to the patient. Result: The patients of major depression disorder had lower scores of WHOQOL-BREF in physical [(10.86±1.73) vs (12.13±1.99], psychological [(10.79±1.62) vs (12.61±1.97)], social [(11.18±2.77) vs (13.45±2.79)], environment [(12.50±2.13) vs (13.84±2.24)] domains than the other patients. Correlation analysis showed that scores of WHOQOL-BREF was correlated with scores of HAMA,PHQ-9andSDS-work.Multi regression analysis showed that marita, medical hist0ry, scores of PHQ-9, SDS-work.

Conclusion  : The quality of life of depression is obviously lower than normal people. The heavier degree of patients with depression, the longer the history, the more serious the function defect, worse quality of life. Another age, gender, comorbidity, drinking, history also affect different aspects of the patient’s quality of life. Intervention according to related factors, to improve the patient’s quality of quality.

Key words: 【Key words】Patients with depression; Quality of life.

引用本文 / How to Cite This Article

郑晓静,王传跃,周福春.综合医院心身门诊重性抑郁症患者生活质量和影响因素分析[J]. 国际精神病学杂志, , (): -

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