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阿立哌唑与认知行为联合应用于首发精神分裂症患者对认知功能的改善作用

  • 杨巍,聂云,李锦光,张焱,曹威

* 通信作者: 曹威, 单位:华中科技大学同济医学院附属武汉市精神卫生中心

摘要

【摘要】
目的 为有效改善精神分裂症患者认知功能,探讨阿立哌唑、认知行为联合应用治疗对患者认知功能的改善效果。

方法 选取2013年3月至2014年6月期间经诊断为首发精神分裂症入院治疗的70例患者,按照病床单双号分为药物对照组35例、联合组35例。药物对照组口服阿立哌唑,联合组在此基础上进行认知行为干预,观察两组患者治疗效果。

结果 联合组精神恢复有效率为94.3%较对照组80.0%好,联合组患者疾病症状、认知能力改善程度较对照组好(P<0.05);治疗前两组PANSS、SDSS评分比较差别无意义(P>0.05),治疗后联合组较对照组疗效好(P<0.05)。

结论 临床对精神分裂首发患者采用阿立哌唑、认知行为联合应用治疗疾病,患者认知功能改善效果明显。

关键词:【关键词】首发精神分裂症;认知行为;阿立哌唑;认知能力

ABSTRACT

[Abstract]
Objective:To improve cognitive function in patients with schizophrenia,and explore the improving effect of aripiprazole combined with cognitive behavior therapy on cognitive function in patients.

Methods:70 cases of patients diagnosed as schizophrenia hospitalized from March 2013 to June 2014 were selected,according to single and double beds,the cases were divided into 35 cases of drug control group and 35 cases of combined group.The drug control group oral aripiprazole,combined group with the cognitive behavioral intervention based on drug control group,observed the treatment effect of two patients group.

Results:The effective rate of the combined group was 80%,compared with that of the control group 94.3%,the disease symptoms and cognitive ability of the combined group were better than those of the control group(P<0.05);Before treatment,two groups of PANSS,SDSS scores were compared with no significance (P>0.05),after treatment,the combined group was better than the control group(P<0.05).

Conclusion  :For schizophrenia were treated with aripiprazole combined with cognitive behavior,patients with cognitive function improved significantly.

Key words: [key words]Schizophrenia;Cognitive behavior;Aripiprazole;Cognitive ability

引用本文 / How to Cite This Article

杨巍,聂云,李锦光,张焱,曹威.阿立哌唑与认知行为联合应用于首发精神分裂症患者对认知功能的改善作用[J]. 国际精神病学杂志, , (): -

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