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氟西汀在治疗高血压伴焦虑抑郁中的应用效果评价

  • 尹祖斌,李进 , 段海水 ,唐世友

* 通信作者: 唐世友, 单位:重庆三峡中心医院平湖分院

摘要

摘要
目的 探讨氟西汀在治疗高血压伴焦虑抑郁中的应用效果。

方法 按照入院顺序抽签后随机将100例高血压伴焦虑抑郁患者分为观察组和对照组,两组患者入院后即接受常规降压治疗,观察组患者在此基础上加用盐酸氟西汀胶囊,比较两组治疗效果。

结果 观察组患者降压总有效率均显著高于对照组,差异有统计学意义(P<0.05);观察组患者治疗后SBP和DBP水平均显著低于对照组,差异有统计学意义(P<0.05);观察组患者治疗后SAS和SDS水平均显著低于对照组,差异有统计学意义(P<0.05);观察组患者治疗后血浆NE水平显著低于对照组,血浆5-HT水平显著高于对照组,差异有统计学意义(P<0.05);观察组患者治疗后生活质量各项评分均显著高于对照组,差异有统计学意义(P<0.05)。

结论 氟西汀能够有效提高常规降压方案对高血压伴焦虑抑郁的治疗效果,改善患者焦虑抑郁状态,提高生活质量,应用价值较高。

关键词:关键词 高血压;焦虑抑郁;氟西汀

ABSTRACT

Abstract
Objective To explore the applicative effects of the patients with hypertension associated with anxiety and depression by fluoxetine.

Methods 100 cases of patients with hypertension associated with anxiety were randomly divided into observation group and control group. The two groups were treated by conventional treatment after admission. On the basis of the conventional treatment, the observation group were treated by fluoxetine. The applicative effects were observed.

Results The total effective rate of depressurization for observation group was higher than control group(P<0.05); The level of SBP and DBP after treatment for observation group were lower than control group(P<0.05); The level of SAS and SDS after treatment for observation group were lower than control group(P<0.05); The level of NE after treatment for observation group was lower than control group(P<0.05); The level of 5-HT after treatment for observation group was higher than control group(P<0.05); The score of living quality after treatment for observation group were higher than control group(P<0.05).

Conclusion   It can improve the applicative effects of the patients with hypertension associated with anxiety and depression by conventional treatment, improve the anxiety and depression, living quality. It has higher application value.

Key words: Keywords Hypertension associated; Anxiety and depression; Fluoxetine

引用本文 / How to Cite This Article

尹祖斌,李进 , 段海水 ,唐世友.氟西汀在治疗高血压伴焦虑抑郁中的应用效果评价[J]. 国际精神病学杂志, , (): -

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