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脑卒中急性期患者卒中后抑郁的发生率及相关因素的研究

  • 石杰,邱红,艾永梅,陈捷

* 通信作者: 石杰, 单位:大庆市第五医院

摘要

摘要:
目的 分析急性期的脑卒中患者卒中后抑郁的发生率与影响因素。

方法 随机选取2014年5月2016年5月在我院住院治疗的处于急性期的脑卒中患者160例,依据其是否发生卒中后抑郁分组,包含抑郁组与非抑郁组。搜集全部患者的一般资料,诊断脑卒中发病状况,评价神经功能缺损程度,检测超敏C-反应蛋白(hs-CRP),分析卒中后抑郁的发生率和影响因素。

结果 脑卒中患者中卒中后抑郁发生率是46.25%(74例),其中轻度是54.05%(40/74),中度是28.38%(21/74),重度是17.57%(13/74)。是否存在基本疾病高血压、糖尿病和高尿酸血症、肥胖的脑卒中患者的卒中后抑郁发生率存在显著的差异(P<0.05),不同病灶位置与高敏 C-反应蛋白的脑卒中患者的卒中后抑郁发生率存在显著的差异(P<0.05),抑郁组的NIHSS评分明显高于非抑郁组,两组存在统计学上的差异(P<0.05)。经多因素分析,脑卒中患者卒中后抑郁的独立高危因素包含病灶位置、高血压、肥胖、NIHSS与高敏 C-反应蛋白(P<0.05)。

结论 脑卒中患者的卒中后抑郁发病率较高,在脑卒中的急性期主要是中度和轻度,脑卒中患者卒中后抑郁的独立高危因素有病灶位置、高血压、肥胖、NIHSS与高敏 C-反应蛋白,在临床中应对符合上述因素的脑卒中患者进行早期预防干预,降低卒中后抑郁的发生。

关键词:关键词:急性期;脑卒中;卒中后抑郁;发生率;影响因素

ABSTRACT

Abstract:
Objective To analyze the incidence and related factors of acute stroke patients with depression after stroke.

Methods 160 patients with acute stroke were selected randomly in our hospital from May 2014 to May 2016. They were divided into depression group and non depression group by post-stroke depression. The general information of all patients was collected. the state of stroke, nerve function defect degree, high sensitive C- reactive protein (hs-CRP) levels was diagnosed, and prevalence and related factors of depression after acute cerebral stroke was analyzed.

Results The incidence of post-stroke depression was 46.25% (n = 74), 54.05%(40/74) of them were slightly depressed, 28.38% (21/74) of them were moderately depressed, and 17.57% (13/74) of them were severely depressed. The incidence of post-stroke depression had significant difference with or without concurrent hypertension, diabetes, hyperuricemia, and obesity (P<0.05). The incidence of post-stroke depression had significant difference with different lesion location and high sensitive C- reactive protein (P<0.05). The score of NIHSS in depression group was significantly higher than that in non depression group(P<0.05). By multiple factor analysis, independent risk factors of acute stroke patients with depression after stroke included hypertension, obesity, lesion location, NIHSS and high sensitive C- reactive protein (P<0.05).

Conclusion   The incidence rate of acute stroke patients with depression after stroke is high, mostly in moderate and mild. independent risk factors of acute stroke patients with depression after stroke included hypertension, obesity, lesion location, NIHSS and high sensitive C- reactive protein. The early prevention and intervention should be took to reduce the incidence of post-stroke depression in the clinic.

Key words: Key words: acute; stroke; post-stroke depression; incidence; related factors

引用本文 / How to Cite This Article

石杰,邱红,艾永梅,陈捷.脑卒中急性期患者卒中后抑郁的发生率及相关因素的研究[J]. 国际精神病学杂志, , (): -

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