【摘要】

[摘 要] 目的 探讨帕罗西汀对广泛型焦虑障碍的治疗效果及对患者睡眠质量的影响。
方法 回顾性分析2015年3月-2016年5月在我院接受治疗的广泛型焦虑障碍患者的临床资料，根据其治疗方式分为喹硫平治疗组（对照组）和帕罗西汀药物治疗组（观察组）。观察两组患者的治疗效果，比较两组患者治疗前后HAMA、TESS评分、睡眠质量的差异。
结果 观察组治疗的有效率为97.87%，明显高于对照组（χ2值=4.106，P=0.043）；两组患者治疗前HAMA、TESS评分无差别，治疗后，观察组的HAMA、TESS评分均低于对照组（t=4.651、16.548，P<0.001）；两组患者治疗前睡眠质量无差别，治疗后，观察组的睡眠质量、入睡时间和睡眠时间均优于对照组。
结论 帕罗西汀对广泛型焦虑障碍有较好的治疗效果，可明显改善患者的焦虑抑郁症状，提高患者的睡眠质量，具有临床应用的价值。

【Abstract】

Abstract: Objective To investigate the effect of Pa Rossi Dean on the treatment of generalized anxiety disorder and the effect on sleep quality.
Methods Retrospective analysis of clinical data of patients with generalized anxiety disorder in March 2015 to May 2016 in our hospital, according to the treatment methods are divided into Quetiapine group (control group) and paroxetine treatment group (observation group). The therapeutic effects of the two groups were observed, and the differences of HAMA, TESS score, sleep quality and adverse events were compared between the two groups before and after treatment.
Results In the observation group, the treatment efficiency was 97.87%, significantly higher than the control group (2 =4.106, P=0.043); Two groups of patients before treatment, HAMA, TESS score no difference, after treatment, the observation group of HAMA, TESS score were lower than the control group (t=4.651, 16.548, P<0.001); There was no difference in sleep quality between the two groups before treatment. After treatment, the sleep quality, sleep time and sleep time of the observation group were better than those of the control group.
Conclusion   Pa Rossi Dean has a good effect on the treatment of generalized anxiety disorder, can significantly improve the symptoms of anxiety and depression, improve the sleep quality of patients, and has the value of clinical application.