本刊首页 > 期刊目次 > 影响精神分裂症患者停止治疗的相关因素研究

• 文章 •

影响精神分裂症患者停止治疗的相关因素研究

  • 杨淑珍,赵晶媛,华婷婷,艾小青,顾小静

* 通信作者: 赵晶媛, 单位:新乡医学院第二附属医院精神七科

摘要

新乡医学院第二附属医院精神七科 河南新乡453002; 【摘要】
目的 探索对精神分裂症患者停止治疗的相关影响因素评价,从而对精神分裂症患者疾病症状、治疗方案等提供有效信息。

方法 选取2014年1月至2016年6月于我院接受治疗的92例精神分裂症患者为研究对象,并于开始治疗2个月后采用阳性与阴性症状量表(PANSS)对患者进行评价,评定精神症状的有无及各项症状的严重程度。对可能造成精神分裂症患者停止治疗的因素进行单因素分析,并将确定的相关可能因素进行多因素Logistic回归分析。

结果 本次研究中患者第1~3个月阳性与阴性症状量表(PANSS)评分不断下降,分别为(83.12±21.48)分、(64.15±20.19)分,患者接受棕榈酸帕利哌酮注射液注射治疗后病情得到明显改善,但是第3个月后患者阳性与阴性症状量表(PANSS)评分不断上升,患者精神分裂症病情不断加重。对可能影响精神分裂症患者停止治疗的单因素

结果分析得出,PANSS分数、性别、第3针剂量以及使用其他抗精神类药物是造成精神分裂症患者停止治疗的相关因素。Logistic回归分析显示PANSS分数、女性患者、第3针剂量以及使用其他抗精神病药物是造成精神分裂症患者停止棕榈酸帕利哌酮注射液注射治疗的独立危险因素。

结论 精神分裂症患者性别、患者第3剂棕榈酸帕利哌酮注射液剂量等是造成精神分裂症患者棕榈酸帕利哌酮注射液停止治疗的可能因素。

关键词:【关键词】 精神分裂症;停止治疗;症状;影响

ABSTRACT

Abstract】
Objective To explore the relevant factors of the treatment of schizophrenia patients to stop the treatment, so as to provide effective information on the symptoms of schizophrenia, treatment options, etc.

Methods 92 patients with schizophrenia from January 2014 to June 2016 in our hospital treatment were selected as the research object, and 2 months after the start of treatment to the positive and negative symptoms scale (PANSS) to evaluate the patients, the severity of psychiatric symptoms assessed with or without the symptoms. Univariate analysis was performed to determine the factors that may lead to the cessation of treatment in patients with schizophrenia, and the related factors were analyzed by multivariate Logistic regression.

Results This study in patients with 1~3 months of the positive and negative symptom scale (PANSS) score decreased, respectively (83.12 ± 21.48), (64.15 ± 20.19), patients received Paliperidone Palmitate Injection treatment after the disease has been improved significantly, but third months after the positive and negative symptom scale (PANSS) the score is rising, the schizophrenia disease has been increasing. The possible influencing factors of schizophrenia patients stopped treatment results, PANSS score, gender, third dose and other antipsychotic drugs are the factors causing schizophrenia patients to stop treatment. Logistic regression analysis showed that PANSS score, female patients, third dose and the use of other antipsychotic drugs are independent risk factors causing schizophrenia patients stop Paliperidone Palmitate Injection treatment.

Conclusion   The gender of schizophrenia patients, third doses of Paliperidone Palmitate Injection, Paliperidone Palmitate Injection, etc. are the possible factors for the treatment of schizophrenia.

Key words: 【Key words】 Schizophrenia; Stop treatment; symptom; influence

引用本文 / How to Cite This Article

杨淑珍,赵晶媛,华婷婷,艾小青,顾小静.影响精神分裂症患者停止治疗的相关因素研究 [J]. 国际精神病学杂志, , (): -

参考文献

相关文章