【摘要】

摘要：目的：探讨重复经颅磁刺激联合药物治疗抑郁症患者的临床疗效及对应对方式的影响。
方法：选择2014年2月-2016年1月收治的124例抑郁症患者为研究对象，采用随机数字表法分为观察组和对照组各62例，对照组给予帕罗西汀、奥氮平治疗，观察组给予重复经颅磁刺激联合帕罗西汀、奥氮平治疗，治疗12周后，比较两组汉密尔顿抑郁量表（HAMD）评分、临床疗效、应对方式等指标。
结果：观察组密尔顿抑郁量表（HAMD）评分明显低于对照组（P<0.01）；总有效率88.71%明显高于对照组72.58%（P<0.05）；面对评分明显高于对照组，回避和屈服评分明显低于对照组（P<0.05）。
结论：重复经颅磁刺激联合药物治疗有助于改善抑郁症患者的临床症状，形成良好应对方式，提高临床疗效。

【Abstract】

Abstract: Objective: To investigate the effect of repetitive transcranial magnetic stimulation (rTMS) in combination with drug therapy on clinical efficacy and coping modes of depressed patients.
Methods: A total of 124 depressed patients admitted to hospital from February 2014 to January 2016 were selected as the research objects, and divided into Observation Group and Control Group using the random number table method, with 62 cases in each group. Patients in Control Group were treated by paroxetine and olanzapine, and those in Observation Group were treated by rTMS in combination with paroxetine and olanzapine. After 12 weeks of treatment, the Hamilton Depression Scale (HAMD) score, clinical efficacy, coping modes and other indexes of the two groups were compared.
Results: The HAMD score in Observation Group was significantly lower than in Control Group(P<0.01); the effective rate was 88.71% and significantly higher than 72.58% in Control Group (P<0.05); the confrontation score was significantly higher than in Control Group, and the scores of avoidance and surrender were significantly lower than in Control Group(P<0.05).
Conclusion  : The rTMS in combination with medicine in treating depressed patients is helpful to improve the clinical symptoms, develop favorable coping modes and enhance the clinical efficacy.