【摘要】

【摘要】目的 探讨积极心理干预对阿尔茨海默病（AD）患者药物治疗依从性及精神行为障碍（BPSD）的影响。
方法 选择AD患者94例随机分为两组：对照组（n=47）接受常规护理，观察组（n=47）接受积极心理干预8周。评价简易精神状态量表（MMSE）、阿尔茨海默病评估量表（ADAS）和阿尔茨海默病生命质量测评量表（QOL-AD）评分，比较两组药物治疗依从性。
结果 干预后两组ADAS评分均显著降低，MMSE、QOL-AD评分均显著提高，且观察组改善幅度显著优于对照组（P<0.05）；观察组药物治疗依从率为95.74%，显著高于对照组的82.98%（P<0.05）。
结论 积极心理干预可有效提高AD患者的药物治疗依从性，改善BPSD症状及生活质量。

【Abstract】

【Abstract】 Objective To investigate the effect of positive psychological intervention on compliance with drug therapy and behavioral psychogical symptoms of dementia (BPSD) in patients with Alzheimer's Disease (AD).
Methods 94 cases of AD patients were randomly divided into two groups: The control group (n=47) received routine nursing,the observation group (n=47) received positive psychological intervention on the basis of control group for 8 weeks.The Mini-Mental State Examination (MMSE), Alzheimer's Disease Assessment Scale (ADAS) and Quality of Life-Alzheimer's Disease (QOL-AD) were evaluated,the compliance with drug therapy were compared between the two groups.
Results After invention,the scores of ADAS were significantly decreased, scores of MMSE and QOL-AD were significantly improved in the two groups, the improvements in the observation group were significantly better than the control group (P<0.05). The compliance rate of drug therapy in observation group was significantly higher than the control group (95.74% vs 82.98%,P<0.05).
Conclusion   Positive psychological intervention can effectively improve the compliance of drug therapy of AD patients, improve the BPSD symptoms and quality of life.