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老年原发性H型高血压与认知功障碍的调查研究

  • 曾军燕,张杰,王骐,张娜,王媛,张桂芳

* 通信作者: 张桂芳, 单位:延安大学咸阳医院神经内科

摘要

【摘要】
目的 对老年原发性H型高血压和认知功能障碍进行调查研究。

方法 根据血浆 Hcy 的检测

结果,将80例原发性H型高血压患者设为研究组;将80例非原发性H型高血压患者设为对照组。比较两组一般情况、蒙特利尔认知功能评分量表(MoCA量表)、日常生活能力评定量表( Barthel指数)。

结果 对照组血浆Hcy水平明显低于研究组,差异具有统计学意义(x2=200.000,P<0.05);两组性别、年龄、病程等一般情况比较,差异均无统计学意义(x2=0.029,x2=0.041,x2=0.126,P>0.05)。研究组认知功能总分明显低于对照组,差异具有统计学意义(t=7.283,P<0.05)。对照组Barthel指数>60分的患者32例;研究组Barthel指数>60分的患者19例,明显低于对照组,差异具有统计学意义(x2=6.040,P<0.05);两组Barthel指数≤20分、20~80分、41~60分的患者比较,差异均无统计学意义(x2=1.416,x2=1.579,x2=0.153,P<0.05)。

结论 老年原发性H型高血压可引起患者大脑血管病变,使患者记忆、语言、等认知功能障碍,严重影响患者日常生活能力,临床宜根据患者认知功能障碍特点及血Hcy水平对症治疗,并且积极控制高血压这一危险因素。

关键词:【关键词】老年患者;原发性H型高血压;非原发性H型高血压;认知功能

ABSTRACT

Abstract
Objective: To survey essential type H hypertension and cognitive function disorder of elderly patients. Method: According to results of plasma Hcy detection, 80 cases of patients with essential type H hypertension were set as research group, while other 80 cases of patients with non-essential type H hypertension were set as control group. Patients in two groups were compared for general condition, Montreal Cognitive Assessment (MoCA scale), Activity of Daily living Scale (Barthel index).

Results: Plasma Hcy level of control group was obviously lower than research group, with difference having statistical significance ((x2=200.000,P<0.05), and the difference in gender, age, course of disease and other general conditions between two groups had no statistical significance (x2=0.029,x2=0.041,x2=0.126,P>0.05). The total score of cognitive function in research group was obviously lower than that in control group, with difference having statistical significance (t=7.283,P<0.05). There were 32 cases of patients with a Barthel index over 60 points in control group, and 19 cases of that in research group, which was obviously lower than control group, with difference having statistical significance ((x2=x2=6.040,P<0.05). The difference in Barthel index equal to or below 20 points, 20-60 points and 41-60 points between patients in two groups had no statistical significance (x2=1.416,x2=1.579,x2=0.153,P<0.05).

Conclusion  : Essential type H hypertension of elderly patients can cause brain vascular lesions and disorders in cognitive function like memory and communication, which has strong impact on activity of daily living of patients. Treatment shall be provided in accordance with features of cognitive function disorder and plasma Hcy level of patients in clinic, moreover, hypertension, a risk factor, shall be actively controlled.

Key words: Key words: Elderly patients, Essential type H hypertension, Non-essential type H hypertension, Cognitive function

引用本文 / How to Cite This Article

曾军燕,张杰,王骐,张娜,王媛,张桂芳.老年原发性H型高血压与认知功障碍的调查研究[J]. 国际精神病学杂志, , (): -

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