本刊首页 > 期刊目次 > 无抽搐电休克(MECT)联合氨磺必利治疗精神分裂症阴性症状对临床疗效、阴性因子评分及不良反应的影响

• 文章 •

无抽搐电休克(MECT)联合氨磺必利治疗精神分裂症阴性症状对临床疗效、阴性因子评分及不良反应的影响

  • 周志国

* 通信作者:

摘要

【摘要】
目的 研究精神分裂症阴性症状者应用无抽搐电休克(MECT)和氨磺必利联合治疗对临床疗效、阴性因子评分及不良反应的影响。

方法 前瞻性选取2015年5月-2016年5月本院收治的以精神分裂症阴性症状为主92例患者临床资料进行分析,按照临床所用不同治疗方案分成2组,将应用单纯氨磺必利医治46例患者作为对照组,将应用MECT和氨磺必利联合医治46例患者作为观察组,对两组临床疗效、阴性因子评分及不良反应情况进行对比。

结果 观察组医治后14w背数记忆、再认、联想与图片评分均比对照组优(P<0.05);观察组于两组医治第4w、8w阴性因子评分均改善基础上,其改善幅度均比对照组显著(P<0.05);两组医治后总不良反应率4.35%、8.70%对比无明显差异(P>0.05)。

结论 精神分裂症阴性症状者应用MECT和氨磺必利联合医治能够提高记忆能力,改善患者阴性因子评分,且不良反应少,具有临床推广及应用价值。 【关键词】阴性症状;精神分裂症;无抽搐电休克;氨磺必利;不良反应

关键词:【关键词】阴性症状;精神分裂症;无抽搐电休克;氨磺必利;不良反应

ABSTRACT

[Abstract]
Objective: To survey the effect of combining electroconvulsive therapy (MECT) with amisulpride on the treatment of schizophrenia negative symptoms to clinical efficacy, negative factor score and adverse reactions.

Methods: The clinical data of 70 cases of patients with schizophrenia negative symptoms treated in our hospital from May 2015 to May 2016 were analyzed prospectively. Divided the 70 patients into two groups based on different clinical treatment methods. 35 cases of patients treated by amisulpride only were regarded as the control group. The other 35 cases treated by combining MECT with amisulpride were regarded as the observation group. The clinical efficacy, negative factor score and adverse reactions of the two groups were taken into comparison. Result: The number memory, recognition, association and image score of the treatment conditions of observation group in the second week was superior than that of the control group(P<0.05); On the basis of the negative factor score improved, the improvement extent of the treatment conditions of the observation group in the fourth and eighth week was superior than that of the control group (P<0.05); The total adverse reaction rate of the two groups after being treated was 5.71%、11.43% and no obvious contrast difference existed.

Conclusion  : Adopt combining electroconvulsive therapy with amisulpride to cure patients with schizophrenia negative symptoms can improve memory ability and patients' negative factor score, reduce adverse reactions and owns clinical promotion and application value. 【Keywords】Negative symptoms; schizophrenia; modified electroconvulsive therapy; amisulpride; adverse reactions

Key words: 【Keywords】Negative symptoms; schizophrenia; modified electroconvulsive therapy; amisulpride; adverse reactions

引用本文 / How to Cite This Article

周志国.无抽搐电休克(MECT)联合氨磺必利治疗精神分裂症阴性症状对临床疗效、阴性因子评分及不良反应的影响[J]. 国际精神病学杂志, , (): -

参考文献

相关文章