【摘要】

目的：探讨与比较尿激酶静脉与超选择性动脉溶栓对脑梗死患者的临床效果。
方法：收集我院2013年1月至2015年1月入院的64例脑梗死患者随机分为两组，动脉组患者采用超选择性动脉溶栓治疗，静脉组患者采用尿激酶静脉溶栓治疗，比较两组患者治疗前后神经功能缺损与日常生活能力、近期总体治疗效果、继发出血与死亡情况、远期预后效果等。
结果：动脉组患者治疗后NIHSS评分（5.04±1.57）组间比较显著性低于静脉组（8.20±5.68），BI指数（58.25±10.21）显著性高于静脉组（49.49±9.68），存在显著性差异（t=3.033，3.522），具有统计学意义（P<0.01）；动脉组患者显效率（46.88%）与总有效率（81.25%）均明显高于静脉组（21.88%，59.38%），存在明显差异（χ2=4.433，3.668），具有统计学意义（P<0.05）；动脉组总体出血率（34.38）明显低于静脉组（59.38%），存在明显差异（χ2=4.016），具有统计学意义（P<0.05）；动脉组远期预后良好率（64.52%）明显高于静脉组（37.93%），存在明显差异（χ2=4.241），具有统计学意义（P<0.05）。
结论：超选择性动脉溶栓治疗对脑梗死患者的治疗近期疗效更好，安全性更高，且远期预后较好，具有借鉴性。

【Abstract】

Objective: Research and Comparison of intravenous and super-selective intra-arterial thrombolysis for patients with cerebral infarction clinical results. Method: A hospital from January 2013 to January 2015 64 cases of hospitalized patients with cerebral infarction were randomly divided into two groups, artery group were treated with super-selective intra-arterial thrombolysis therapy group were treated with intravenous thrombolytic therapy with urokinase, comparison of two groups of patients before and after treatment neurological deficit and activities of daily living, the recent overall treatment effect, secondary bleeding and death, and so the long-term prognosis. Result: The arterial patient group after treatment NIHSS score (5.04 ± 1.57) between the two groups was significantly lower than the intravenous group (8.20 ± 5.68), BI index (58.25 ± 10.21) was significantly higher than the intravenous group (49.49 ± 9.68), there was a significant difference (t = 3.033,3.522), a statistically significant (P <0.01); significant efficiency artery patients (46.88%) and overall response rate (81.25%) were significantly higher than the intravenous group (21.88%, 59.38%) , there are significant differences (χ2 = 4.433,3.668), a statistically significant (P <0.05); overall bleeding rates artery group (34.38) was significantly lower than the intravenous group (59.38%), there are significant differences (χ2 = 4.016), having statistically significant (P <0.05); artery group long-term prognosis is good rate (64.52%) was significantly higher than the intravenous group (37.93%), there are significant differences (χ2 = 4.241), a statistically significant (P <0.05).
Conclusion  : super selective arterial thrombolysis therapy for patients with cerebral infarction curative effect better, more secure, and the long-term prognosis is good, with Reference.