【摘要】

目的 探讨睡眠障碍合并抑郁症患者的认知受损情况及其影响因素。
方法 选取我院确诊的160例睡眠障碍患者，其中60例合并抑郁症作为A组、单纯睡眠障碍100例作为B组，收集时间2014年11月至2016年9月，采用重复性成套神经心理状态测验（RBANS）评估两组患者的认知功能，并采用多因素
方法探讨对患者认知功能损害的相关因素。
结果 A组患者的即刻记忆、视觉广度、言语功能、注意力、延时记忆、RBANS总分均显著的低于B组患者，差异具有统计学意义（P<0.05）； A组患者认知功能障碍检出率46.67%显著的高于B组患者的7.00%，差异具有统计学意义（P<0.05）；颈动脉狭窄、睡眠障碍病程延长、合并抑郁症时睡眠障碍患者并发认知功能障碍的独立危险因素（OR=2.296、OR=1.574、OR=1.309，P<0.05）。
结论 睡眠障碍合并抑郁症将会进一步加大对患者认知功能的损害，因此必须重视对患者抑郁病情的治疗。

【Abstract】

Objective To investigate the cognitive impairment of patients with sleep disorders and depression and its influencing factors.
Methods A total of 160 patients with sleep disorders were enrolled in this study. Among them, 60 patients with depression were treated as group A and 100 patients with simple sleep disorder as group B, and were collected from November 2014 to September 2016. The patients were diagnosed with repetitive neuropsychological status (RBANS) were used to evaluate the cognitive function of the two groups, and the factors related to the cognitive impairment were explored by multivariate method.
Results A group of patients with immediate memory, breadth of vision, speech function, attention, delayed memory, the total score of RBANS was significantly lower than that in B group, the difference was statistically significant (P<0.05); A group of cognitive impairment in patients with the detection rate of 46.67% was significantly higher than that in B group were 7%, the difference was statistically significant (P<0.05); independent risk cognition dysfunction complicated with sleep disorders in patients with carotid artery stenosis, and factors associated with depression sleep disorder duration prolonged when (OR=2.296, OR=1.574, OR=1.309, P<0.05).
Conclusion   Sleep disorders associated with depression will further increase the cognitive impairment of patients, so we must pay attention to the treatment of patients with depression.