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躯体化障碍针灸治疗后P300及睡眠脑电的变化

  • 李小平,宋立升

* 通信作者: 宋立升, 单位:上海市精神卫生中心

摘要


目的 探讨事件相关电位P300及Quisi在躯体化障碍患者睡眠障碍评估中的价值。

方法 应用脑电生理仪对91例躯体化障碍患者分别在治疗前和治疗后7周进行P300和Quisi检测,使用匹兹堡睡眠质量指数量表(PSQI)等测定患者的睡眠障碍。

结果 (1)纳入研究的91例SFD中,依症状出现频率由高到低依次为睡眠、认知功能、心血管系统、运动系统、消化系统、泌尿生殖系统、呼吸系统及五官不适症状。(2)治疗前躯体化障碍组有明显的睡眠缺损,其PSQI≥14分。P300表现为P3靶潜伏期延长,靶P2、P3波幅低,非靶P2波幅低(P<0.01),同时Quisi异常。治疗后,随着躯体化障碍患者的睡眠的恢复,其P300主要表现为P3潜伏期缩短,P3波幅增高及Quisi有所恢复(P<0.05~0.01)。

结论 针灸能改善睡眠质量。Quisi及P300联合运用有助于反映躯体化障碍患者睡眠的变化,Quisi及P3指标的变化较有临床应用价值。

关键词:躯体化障碍; P300;Quisi;睡眠障碍;针灸治疗

ABSTRACT

objective To study event-related potentials P300 and Quisi changes in patients with somatoform disorders for evaluation of their sleep disorder.

Methods 91 patients were enrolled in the study, the high to low frequency of symptoms of SFD were the symptoms of sleep, cognitive function, cardiovascular system, motor system, digestive system, urogenital system, respiratory system, and facial features. With Nicolet USA Instrument, P300 and Quisi test and pittsburgh sleep quality index (PSQI) assessment were carried out in 91 patients met ICD-10 criteria of somatoform disorders 7 weeks before and after treatment; and 91normally aged controls served as the control group.

Results Before treatment, the score of PSQI in the Insomnia patients was lower than that in the control group (P<0.01). somatoform disorders patients had significant delayed P3 latencies and decreased P2 and P3 amplitudes of P300 as compared with the control group (P<0.01). After 7-week treatment, Insomnia patients had remarkable shortened P3 latency and increased P3 amplitude.

Conclusion   Acupunture therapy belongs to a new antipsychotic and be useful to sleep. Quisi and P300 indexes, especially P3 latency, might be useful in inspecting sleep disorder changes in somatoform disorders patients.

Key words: Somatoform Disorders; P300; Quisi; Sleep disorder;Acupunture therapy

引用本文 / How to Cite This Article

李小平,宋立升.躯体化障碍针灸治疗后P300及睡眠脑电的变化[J]. 国际精神病学杂志, , (): -

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