【摘要】

目的 探究三叉神经痛（TN）经射频热凝术（PRF）治疗的远期疗效、分析影响疗效的相关因素。
方法 将104例三叉神经痛患者随机分为PRF治疗组（P组）和药物治疗组（N组），两组各52例。P组患者在CT引导下行三叉神经半月神经节射频热凝术，N组予以卡马西平治疗，观察两组患者疗效并进行随访。记录随访
结果，包括远期疗效、并发症发生情况、复发率和影响三叉神经痛治疗效果的相关因素。
结果 P组总有效率（92.31%）高于N组（65.38%），并发症发生率（13.46%）、复发率（3.85%）则均低于N组（32.69%，15.38%）（P﹤0.05），经logistics多因素回归分析
结果显示，年龄、病程、症状、分支数、治疗方式是影响三叉神经痛的远期预后不佳的独立危险因素。
结论 射频热凝术可长期有效缓解三叉神经痛患者的病情，同时可预防并发症发生，不易复发；患者年龄、病程、症状、分支数、治疗方式可影响治疗效果及复发，应予以重视。

【Abstract】

Objective To investigate the long term curative effect and the relative factors affecting the curative effect of TN after radio frequency thermocoagulation(PRF).
Methods 104 patients with trigeminal neuralgia were randomly divided into PRF group(group P) and drug group(group N), 52 cases each. Radiofrequency thermocoagulation of trigeminal ganglion was performed in group P under CT guidance. Camaxepine was treated in group N. The results of follow-up were recorded, including long-term curative effect, complications, recurrence rate and related factors affecting the therapeutic effect of trigeminal neuralgia.
Results The total efficiency of group P(92.31 %) was higher than group N(65.38 %), the incidence of complications(13.46 %) and recurrence rate(3.85 %) were lower than group N(32.69 %, 15.38 %)(P 0.05).
Conclusion