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糖尿病合并高血压患者肾功能与心血管事件相关性研究

  • 杨群峰,罗恩斯,曹绮雯

* 通信作者: 杨群峰, 单位:东莞市第五人民医院 523900

摘要

【摘要】
目的:研究糖尿病合并高血压患者肾功能与心脑血管事件相关性。

方法:我院2014年12月-2015年12月期间共收治糖尿病合并高血压患者1000例,以患者1年内是否发生心脑血管事件为依据将其分为事件组和无事件组,事件组患者368例,无事件组患者632例,对比分析两组糖尿病合并高血压患者肾功能情况对其新发心血管事件的影响。

结果:368例新发心血管事件中,脑血管病发生率最高,可达24.18%。事件组患者年龄较大、舒张压低、脉压高、空腹血糖值高和估算肾小球滤过率低,与无事件组相比,差异具有显著性(P<0.05);随着患者肾小球滤过率的降低,特别是当肾小球滤过率<40ml/min-1.732时,全因死亡和心血管事件发生率显著增加,组间对比,差异具有显著性(P<0.05)。

结论:对于老年糖尿病合并高血压患者而言,收缩压、总胆固醇、患者体重指数的增加与患者心血管事件的发生无明显相关性。估算肾小球滤过率和年龄是导致患者发生心血管事件的独立危险因素。

关键词:【关键词】糖尿病 高血压 肾功能不全 心血管事件 相关性

ABSTRACT

【 abstract 】 objective: to study the renal hypertension patients with diabetic cardiovascular event correlation.

Methods: our hospital during the period of December 2014 - December 2015 treated 1000 cases of patients with high blood pressure, diabetic in patients in recent 1years are based on cardiovascular events will be divided into the event group and no event group, the event group, 368 cases of patients, 632 cases of patients with event group, compared two groups of diabetic renal function in patients with high blood pressure on its new cardiovascular events.

Results: of 368 cases of new cardiovascular events, the highest incidence of cerebrovascular disease, can amount to 24.18%. Event group in patients with older age, low diastolic, high pulse pressure, high fasting blood glucose value and estimated glomerular filtration rate is low, compared with no event group, with significant difference (P < 0.05); With the loss of the patients with glomerular filtration rate, especially when the glomerular filtration rate < 40 ml/min - 1.732, all due to the significantly higher rates of death and cardiovascular events, comparison between groups, with significant difference (P < 0.05).

Conclusion  : in elderly diabetes mellitus patients with hypertension, blood pressure, blood lipid, blood glucose and body mass index in patients with increased with the incidence of cardiovascular events in patients with no significant correlation. Estimated glomerular filtration rate and age are independent risk factors of cardiovascular events in patients with.

Key words: 【 key words 】 diabetes high blood pressure, renal insufficiency cardiovascular event correlation

引用本文 / How to Cite This Article

杨群峰,罗恩斯,曹绮雯.糖尿病合并高血压患者肾功能与心血管事件相关性研究[J]. 国际精神病学杂志, , (): -

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