本刊首页 > 期刊目次 > 冠状动脉粥样硬化性心脏病患者应用阿托伐他汀联合阿司匹林的效果观察及对患者SF-36的影响

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冠状动脉粥样硬化性心脏病患者应用阿托伐他汀联合阿司匹林的效果观察及对患者SF-36的影响

  • 李亚丽

* 通信作者: 李亚丽, 单位:云南临沧市人民医院

摘要

摘要:
目的:研究冠状动脉粥样硬化性心脏病患者应用阿托伐他汀联合阿司匹林的治疗效果及对患者健康调查简表(SF-36)评分的影响。

方法:本研究于2016年3月~2017年3月选取了院内收治的110例冠状动脉粥样硬化性心脏病患者作为研究对象,随机分为治疗组和对照组,对照组给予阿司匹林单独治疗,治疗组在对照组基础上联用阿托伐他汀进行治疗,对比两组患者的治疗效果及对患者SF-36的影响。

结果:治疗组的治疗总有效率为96.36%,高于对照组的81.82%(P<0.05);治疗组的用药不良反应率7.3%,对照组21.8%,P值低于0.05,在临床指标方面,治疗组同样比对照组要好,P值低于0.05,;治疗组治疗后的各项SF-36评分均明显高于对照组(P<0.05)。

结论:阿托伐他汀联合阿司匹林可以有效应用于冠状动脉粥样硬化性心脏病患者的临床治疗中,改善患者的临床症状,促进患者生活质量的提升,宜广泛应用和推广。

关键词:冠状动脉粥样硬化心脏病;阿托伐他汀;阿司匹林;健康

ABSTRACT

Abstract:
Objective: To investigate the therapeutic effect of atorvastatin combined with aspirin in patients with coronary atherosclerotic heart disease and the effect on the MOS item short from health survey(SF-36)score.

Methods:110 cases with coronary atherosclerotic heart disease were selected in our hospital from March 2016 to March 2017as subjectinvestigated. The patients were randomly divided into treatment group and control group. The control group was treated with aspirin alone and the treatment group was given atorvastatin combined with aspirin.Then the effect of the clinical treatment and the change of SF-36 score were compared between the two groups.

Results: The total effective rate in the treatment group was higher than that of in the control group (96.36% vs.81.82% ,P <0.05). The incidence of side effects in the treatment group was lower than that of in the control group (7.3%vs.21.81%, P <0.05);the clinical indexes of the treatment group were significantly better than the control group (P<0.05). The scores ofSF-36 entries in the treatment group were significantly higher than those of in the control group (P<0.05).

Conclusion  : Atorvastatin combined with aspirin can be effectively applied in the clinical treatment of patients with coronary atherosclerotic heart disease. The therapeutic regimen can not only improve the clinical symptoms but also promote the improvement of quality of life of patients,hence it isworth spread and application.

Key words: Coronary atherosclerotic heart disease; Atorvastatin; Aspirin; Health

引用本文 / How to Cite This Article

李亚丽.冠状动脉粥样硬化性心脏病患者应用阿托伐他汀联合阿司匹林的效果观察及对患者SF-36的影响[J]. 国际精神病学杂志, , (): -

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