摘要

目的 探讨口腔扁平苔藓伴焦虑抑郁状态患者给予舍曲林联合心理治疗后效果。

方法 将我院83例口腔扁平苔藓伴焦虑抑郁状态患者采用随机数字表法分组，两组患者均给予常规对症治疗，对照组41例患者增加心理治疗，观察组42例在对照组基础上增加舍曲林口服治疗，对比两组患者治疗后症状体征评分变化、焦虑、抑郁情绪转变情况、生活质量改变，并对比临床疗效。

结果 治疗后，观察组总有效率90.48%高于对照组的73.17%，VAS、SAS、REU、SDS及OHIP-14评分均低于对照组（P<0.05）。

结论 舍曲林联合心理治疗能够有效改善口腔扁平苔藓伴焦虑抑郁患者症状体征，缓解患者焦虑抑郁情绪，促进患者生活质量提升。

关键词：舍曲林；心理治疗；口腔扁平苔藓；焦虑抑郁；生活质量；情绪

ABSTRACT

Objective To investigate the effect of sertraline combined with psychotherapy in patients with oral lichen planus with anxiety and depression.

Methods Eighty-three patients with oral lichen planus with anxiety and depression were grouped by random number table in our hospital. The two groups were given conventional symptomatic treatment, 41 patients in the control group were added with psychological therapy, and 42 patients in the observation group were given homes. Tralin was treated orally to compare the changes in symptoms and signs scores, changes in anxiety, depression, and quality of life between the two groups of patients, and compare the clinical efficacy.

Results After treatment, the total effective rate in the observation group was 90.48% higher than the control group's 73.17%, and the VAS, SAS, REU, SDS, and OHIP-14 scores were all lower than the control group (P <0.05).

Conclusion   Sertraline combined with psychotherapy can effectively improve the symptoms and signs of patients with oral lichen planus with anxiety and depression, relieve the patient's anxiety and depression, and promote the improvement of patients' quality of life.

Key words: sertraline; psychotherapy; oral lichen planus; anxiety and depression; quality of life; emotions