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舍曲林辅助治疗室性心律失常患者的效果及对负面情绪的影响

  • 赵素贞

* 通信作者: 赵素贞, 单位:漯河市召陵区人民医院

摘要

【摘要】
目的 探究舍曲林辅助治疗室性心律失常患者的效果及对负面情绪的影响。

方法 选取2017年6月-2019年10月期间90例室性心律失常患者,根据随机数字表法分组。对照组45例给予胺碘酮治疗,观察组45例增加舍曲林辅助治疗,2个月后,对比两组患者室性心律失常次数、心律变异性指标、焦虑抑郁情绪、睡眠质量及不良反应。

结果:治疗后观察组室性心律失常次数、HAMA、HAMD、PSQI评分低于对照组,SDNN、SDANN、RMSSD、PNN50均高于对照组,有统计学意义(P<0.05)。观察组不良反应发生率为8.89%高于对照组6.67%,无统计学意义(P>0.05)。

结论:舍曲林辅助治疗室性心律失常患者,可降低室性心律失常次数,促进心功能恢复,改善焦虑抑郁负面情绪,药物安全性高。

关键词:【关键词】舍曲林;室性心律失常;负面情绪

ABSTRACT

【Abstract】
Objective To explore the effect of sertraline in adjuvant treatment of patients with ventricular arrhythmia and its influence on negative emotions.

Methods From June 2017 to October 2019, 90 patients with ventricular arrhythmia were selected and grouped according to the random number table method. 45 patients in the control group were treated with amiodarone, and 45 patients in the observation group were treated with adjuvant sertraline. Two months later, the number of ventricular arrhythmia, heart rhythm variability indicators, anxiety and depression, sleep quality and adverse reactions were compared between the two groups .

Results: After treatment, the number of ventricular arrhythmias, HAMA, HAMD, and PSQI scores in the observation group were lower than those in the control group. SDNN, SDANN, RMSSD, and PNN50 were all higher than those in the control group, with statistical significance (P<0.05). The incidence of adverse reactions in the observation group was 8.89% higher than that in the control group 6.67%, which was not statistically significant (P>0.05).

Conclusion  : Sertraline adjuvant treatment of patients with ventricular arrhythmia can reduce the frequency of ventricular arrhythmia, promote heart function recovery, improve anxiety and depression and negative emotions. The drug is safe.

Key words: [Keywords] Sertraline; ventricular arrhythmia; negative emotions

引用本文 / How to Cite This Article

赵素贞.舍曲林辅助治疗室性心律失常患者的效果及对负面情绪的影响[J]. 国际精神病学杂志, 2021, 48(4): 700-702

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