本刊首页 > 期刊目次 > 氟西汀辅助治疗糜烂溃疡性口腔黏膜病的效果及对患者焦虑抑郁情绪及生活质量的影响

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氟西汀辅助治疗糜烂溃疡性口腔黏膜病的效果及对患者焦虑抑郁情绪及生活质量的影响

  • 弓飞

* 通信作者: 弓飞, 单位:郑州颐和医院口腔科

摘要

【摘要】
目的 探究糜烂溃疡性口腔黏膜病患者应用氟西汀辅助治疗后疗效及对患者情绪与生活质量的影响。

方法 选取我科2018年3月-2020年6月期间85例糜烂溃疡性口腔黏膜病患者进行研究,通过掷币法将患者分组,入组患者均给予常规对症治疗,常规组患者42例联合心理治疗,联合组患者43例增加氟西汀口服治疗,记录并对比两组患者治疗前及治疗30d后焦虑抑郁情绪、症状变化、临床疗效及生活质量改变。

结果:联合组临床疗效、SF-36评分高于常规组,SAS、VAS、SDS、REU评分及创面愈合时间均低于常规组(P<0.05)。

结论:在常规治疗基础上联合氟西汀,能够有效缩短糜烂溃疡性口腔黏膜病患者病损创面愈合时间,减轻疼痛,消除焦虑抑郁情绪,提升治疗效果,改善生活质量。

关键词:【关键词】氟西汀;糜烂溃疡性;口腔黏膜病;焦虑抑郁;生活质量

ABSTRACT

[Abstract]
Objective To explore the effects of fluoxetine adjuvant therapy on patients with erosive ulcer oral mucosal disease and their effects on mood and quality of life.

Methods A total of 85 patients with erosive ulcer oral mucosal disease in our department from March 2018 to June 2020 were selected for research. The patients were divided into groups by coin toss. All patients in the group were given conventional symptomatic treatment, and 42 patients in the conventional group were combined with psychology. For treatment, 43 patients in the combined group were given oral fluoxetine treatment. The anxiety and depression mood, changes in symptoms, clinical efficacy and quality of life were recorded and compared between the two groups before treatment and 30 days after treatment.

Results: The clinical efficacy and SF-36 scores of the combined group were higher than those of the conventional group, and the SAS, VAS, SDS, REU scores and wound healing time were lower than those of the conventional group (P<0.05).

Conclusion  : Combining fluoxetine on the basis of conventional treatment can effectively shorten the wound healing time of patients with erosive ulcerative oral mucosal disease, relieve pain, eliminate anxiety and depression, enhance the treatment effect, and improve the quality of life.

Key words: [Keywords] fluoxetine; erosive ulcer; oral mucosal disease; anxiety and depression; quality of life

引用本文 / How to Cite This Article

弓飞.氟西汀辅助治疗糜烂溃疡性口腔黏膜病的效果及对患者焦虑抑郁情绪及生活质量的影响[J]. 国际精神病学杂志, 2021, 48(4): 703-706

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