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双相障碍患者自杀的危险因素分析

  • 王威,薄奇静,李峰,李田,王传跃

* 通信作者: 薄奇静, 单位:首都医科大学附属北京安定医院 100088

摘要


目的 探讨双相障碍(bipolar disorder,BPD)患者的自杀危险因素。

方法 将参与调查的患者分为伴自杀风险及不伴自杀风险两组,先进行单因素分析,再以自杀风险为因变量,分别以人口学资料和临床特征为自变量,进行多因素Logistic逐步回归分析。

结果 伴自杀风险组的BPD患者出现焦虑症状的比率多于不伴自杀风险组(P<0.001),伴自杀风险组有发病诱因多于不伴自杀风险组(P=0.001),伴自杀风险组患者伴精神病家族史的比率高于不伴自杀风险组 (P=0.016)。多元逻辑回归分析

结果显示:BPD患者自杀的危险因素有伴焦虑症状(P<0.001),及发病前诱因(P=0.005)。

结论 BPD患者中伴有焦虑症状、发病有诱因的患者自杀风险高。

关键词:【关键词】双相障碍;自杀;焦虑症状;危险因素

ABSTRACT


Objective To analyze the risk factors related to suicide in bipolar disorder patients.

Methods The included patients were divided into the group with or without suicide. Univariate analysis were used, then, the factor of suicide was taken as the dependent variable, and the demographic data and clinical characteristics were taken as the independent variables to conduct a stepwise multivariate Logistic regression analysis.

Results The rate of having anxiety symptoms in BPD patients of suicidal risk group was significantly higher than that in the group without suicidal risk (P<0.001), having predisposing factors of the suicidal risk group was significantly higher than that in the group without suicidal risk (P=0.001), and the incidence of family history of mental illness in the group with suicidal risk was significantly higher than that in the group without suicidal risk (P=0.016). The results of multivariate logistic regression analysis were the factors of high suicidal risk were with anxiety symptoms (P<0.001) and with predisposing factors (P=0.005).

Conclusion  s: The BPD patients with suicidal risk who comorbid with anxiety symptoms and predisposition were high.

Key words: 【Keywords】Bipolar disorder; Suicide; Anxiety; Risk factors

引用本文 / How to Cite This Article

王威,薄奇静,李峰,李田,王传跃.双相障碍患者自杀的危险因素分析[J]. 国际精神病学杂志, 2021, 48(4): 640-642

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