摘要

【摘要】
目的：探讨甲状腺癌（thyroid carcinoma，TC）患者切除术后癌因性疲乏现状及与负性情绪、心理弹性的关系。

方法：将我院2022年1月至2023年1月期间收治的85例TC切除术后患者作为研究对象，收集所有TC切除术后患者的一般临床资料，分析不同人口学特征TC切除术后患者的癌因性疲乏情况，采用Spearman相关性分析癌因性疲乏与焦虑情绪、抑郁情绪、心理弹性的相关性，多因素Logistic分析TC切除术后患者的癌因性疲乏的影响因素。

结果：TC切除术后患者癌症疲乏量表（Chronic Fatigue Syndrome，CFS）评分在不同性别、年龄、肿瘤大小、手术方式、病理分期方面比较无显著差异(P>0.05)，在术后放射性碘治疗、焦虑状态、抑郁状态、心理弹性水平方面比较存在显著差异(P<0.05)；Spearman相关性分析显示，CFS评分与汉密尔顿焦虑自评量表（Hamilton Anxiety Scale,HAMA）评分、汉密尔顿抑郁自评量表（Hamilton Depression Scale，HAMD）评分均呈正相关（r=0.305、0.347，P<0.05），与中文版心理弹性量表（Connor- Davidson resilience scale，CD-RISC）评分呈负相关（r=-0.317，P<0.05）；多因素Logistic分析显示，术后放射性碘治疗、焦虑状态、抑郁状态、心理弹性水平均是TC切除术后患者癌因性疲乏的独立影响因素(P<0.05)。

结论：TC切除术后患者癌因性疲乏程度普遍偏高，与抑郁、焦虑负性情绪呈正相关关系，与心理弹性水平呈负相关关系。同时术后放射性碘治疗、负性情绪、心理弹性水平均是TC切除术后患者癌因性疲乏的影响因素。

关键词：【关键词】甲状腺癌；癌因性疲乏；负性情绪；心理弹性

ABSTRACT

[Abstract]
Objective: To explore the current status of cancer-related fatigue in patients with thyroid cancer (TC) after resection and its relationship with negative emotions and psychological resilience. Method: 85 patients who underwent TC resection in our hospital from January 2022 to January 2023 were selected as the study subjects. General clinical data of all patients after TC resection were collected, and the cancer-related fatigue of patients with different demographic characteristics after TC resection was analyzed. Spearman correlation analysis was used to investigate the correlation between cancer-related fatigue and anxiety, depression, and psychological resilience, Multivariate logistic analysis of the influencing factors of cancer-related fatigue in patients after TC resection. Result: There was no significant difference in the Chronic Fatigue Syndrome (CFS) score among patients after TC resection in terms of gender, age, tumor size, surgical method, and pathological stage (P>0.05), but there were significant differences in postoperative radioactive iodine therapy, anxiety state, depression state, and psychological resilience level (P<0.05); Spearman correlation analysis showed that the CFS score was positively correlated with the Hamilton Anxiety Scale (HAMA) score and the Hamilton Depression Scale (HAMD) score (r=0.305, 0.347, P<0.05), and negatively correlated with the Chinese Connor Davidson Resilience Scale (CD-RISC) score (r=-0.317, P<0.05); Multivariate logistic analysis showed that postoperative radioactive iodine therapy, anxiety state, depression state, and psychological resilience level were independent influencing factors for cancer related fatigue in patients after TC resection (P<0.05).

Conclusion  : The degree of cancer-related fatigue in patients after TC resection is generally higher, which is positively correlated with negative emotions such as depression and anxiety, and negatively correlated with psychological resilience level. At the same time, postoperative radioactive iodine therapy, negative emotions, and psychological resilience levels are all influencing factors for cancer related fatigue in patients after TC resection.

Key words: Keywords: Thyroid cancer; Cancer induced fatigue; Negative emotions; Psychological resilience