摘要

【摘要】
目的：研究与分析中晚期肺腺癌化疗患者抑郁情绪状态及影响因素。

方法：选择本院2020年1月～2023年5月中晚期肺腺癌化疗患者196例作为研究对象，采用抑郁自评量表（Self-rating Depression Scale，SDS）评估患者抑郁状态，同时比较不同婚姻状态、化疗认知度、年龄、工作情况、家庭月收入情况、居住地、文化程度、医疗费用支付方式的评估

结果，采用多因素logistic回归分析中晚期肺腺癌化疗患者抑郁情绪状态的影响因素。

结果：本研究中196例中晚期肺腺癌化疗患者存在抑郁情绪者173例（88.27％），无焦虑情绪者23例（11.73％）；不同年龄的中晚期肺腺癌化疗患者存在抑郁情况比较，差异无统计学意义（P＞0.05）；不同婚姻状态、化疗认知度、工作情况、家庭月收入情况、居住地、文化程度、医疗费用支付方式的中晚期肺腺癌化疗患者存在抑郁情况比较，差异有统计学意义（P＜0.05）；采用多因素logistic回归分析

结果显示，婚姻状态、化疗认知度、工作情况、家庭月收入情况、居住地、文化程度、医疗费用支付方式均为中晚期肺腺癌化疗患者抑郁状态的影响因素，差异有统计学意义（P＜0.05）。

结论：中晚期肺腺癌化疗患者抑郁情绪发生率较高，其影响因素包括婚姻状态、化疗认知度、工作情况、家庭月收入情况、居住地、文化程度、医疗费用支付方式等多个方面，今后临床可针对患者抑郁具体影响因素做出针对性调控措施。

关键词：【关键词】抑郁；中晚期肺腺癌；化疗；情绪

ABSTRACT

Objective: To study and analyze the depressive emotional state and influencing factors of chemotherapy patients with advanced lung adenocarcinoma. Method: 196 patients with advanced lung adenocarcinoma undergoing chemotherapy in our hospital from January 2020 to mid May 2023 were selected as the research subjects. The self rating depression scale (SDS) was used to assess the patient's depression status, and the evaluation results of different marital status, chemotherapy awareness, age, work situation, monthly family income, residence, education level, and medical expense payment methods were compared, Multivariate logistic regression analysis was used to investigate the influencing factors of depressive mood in patients with advanced lung adenocarcinoma undergoing chemotherapy. Result: In this study, 173 (88.27%) of the 196 patients with advanced lung adenocarcinoma undergoing chemotherapy had depression, while 23 (11.73%) had no anxiety; There was no statistically significant difference (P>0.05) in the incidence of depression among patients with advanced lung adenocarcinoma undergoing chemotherapy at different ages; There was a statistically significant difference in depression among patients with advanced lung adenocarcinoma undergoing chemotherapy, including different marital status, chemotherapy awareness, work status, monthly family income, place of residence, educational level, and payment methods for medical expenses (P<0.05); The results of multivariate logistic regression analysis showed that marital status, chemotherapy awareness, work status, monthly family income, place of residence, education level, and medical expense payment method were all influencing factors for depression in patients with advanced lung adenocarcinoma undergoing chemotherapy, and the difference was statistically significant (P<0.05).

Conclusion  : The incidence of depression in patients with mid to late stage lung adenocarcinoma undergoing chemotherapy is relatively high. The influencing factors include marital status, chemotherapy awareness, work status, monthly family income, residence, education level, and payment methods for medical expenses. In the future, targeted control measures can be taken in clinical practice to address the specific influencing factors of depression in patients.

Key words: Keywords: Depression; Middle to late stage lung adenocarcinoma; Chemotherapy; emotion