摘要

抑郁症是一种高患病率和高复发率的心理疾病，目前抑郁症的药物、物理以及心理治疗存在一定的局限性，如药物不良反应、治疗费用高、依从性差等。有氧运动是最广泛的抑郁症运动干预类型，也是多个临床指南推荐的治疗手段。本研究综述了有氧运动在抑郁症中的干预作用及其潜在的神经生物学机制、目前研究的进展与局限性，以期为有氧运动在抑郁症的防治方面提供参考依据。

关键词：有氧运动；抑郁症；干预；作用机制

ABSTRACT

Depression is a mental disorder characterized by high morbidity and high recurrence rate, imposing significant psychological and economic burdens. Existing psychological, pharmacological, physical interventions for depression have certain limitations such as adverse drug reactions, high costs, and poor compliance. Exercise intervention, particularly aerobic exercise, is one of the most widely used intervention for depression. Importantly, aerobic exercise is recommended by many clinical guidelines based on its certain advantages like minimal side effects, cost-effectiveness, and controllability. This review summarizes the role and mechanisms of aerobic exercise in the intervention of depression, the progress and limitations of current research, aiming to provide a valuable reference for the development and applications of aerobic exercise in depression.

Key words: Aerobic exercise; Depression; Intervention; Mechanism