摘要

【摘要】
目的 分析认知行为疗法对重症干眼症合并抑郁患者负性情绪、睡眠质量的影响。

方法 选取2023年8月～2024年10月河北省张家口市第四医院门诊就诊的重症干眼症患者150例，抽签随机分为对照组（75例，实施常规心理干预）、研究组（75例，对照组基础上实施认知行为疗法干预）。比较两组眼表疾病指数量表问卷（ocular surface disease index，OSDI）、抑郁自评量表（self-rating depression scale，SDS）、焦虑自评量表（Self-rating Anxiety Scale，SAS）、匹兹堡睡眠指数（Pittsburgh Sleep Quality Index，PSQI）评分及泪膜破裂时间（Break-up Time，BUT）、角膜荧光素染色（corneal fluorescence staining，FL）。

结果 两组干预后的OSDI评分、FL均降低，BUT均升高（P＜0.05）；与对照组干预后相较，研究组OSDI评分、FL更低，BUT更高（P＜0.05）。两组干预后的SAS、SDS评分及PSQI各维度评分均降低（P＜0.05）；与对照组干预后相较，研究组SAS、SDS、PSQI评分更低（P＜0.05）。

结论 认知行为疗法能够有效缓解重症干眼症患者负性情绪，改善其睡眠质量。

关键词：【关键词】 认知行为疗法；干眼症；抑郁状态；负性情绪；睡眠质量

ABSTRACT

【Abstract】
Objective To analyze the effect of cognitive behavioral therapy on negative emotions and sleep quality in patients with severe dry eye syndrome complicated with depression.

Methods Select 150 patients with severe dry eye syndrome who visited the outpatient department of the Fourth Hospital of Zhangjiakou City, Hebei Province from August 2023 to October 2024, Randomly divided by drawing lots into a control group (75 cases, receiving routine psychological intervention) and a study group (75 cases, receiving cognitive-behavioral therapy intervention on the basis of the control group). Compare the scores of the Ocular Surface Disease Index (OSDI) questionnaire, Self Rating Depression Scale (SDS), Self Rating Anxiety Scale (SAS), Pittsburgh Sleep Quality Index (PSQI) and Tear Break Time (BUT), Corneal Fluorescence Staining (FL), between two groups.

Results After intervention, both groups showed a decrease in OSDI score and FL, and an increase in BUT (P<0.05); Compared with the control group after intervention, the study group had lower OSDI scores, FL, and higher BUT (P<0.05).After intervention, the SAS, SDS scores, and PSQI scores in all dimensions decreased in both groups (P<0.05); Compared with the control group after intervention, the study group had lower SAS, SDS, and PSQI scores (P<0.05).

Conclusion   Cognitive behavioral therapy can effectively alleviate negative emotions in patients with severe dry eye syndrome and improve their sleep quality.

Key words: 【Key words】 Cognitive behavioral therapy; Xerophthalmia; Depressive state; Negative emotions; Sleep quality