摘要

【摘要】
目的 分析稳定期双相情感障碍患者生活质量现状，探究患者生活质量与社会功能的相关性。

方法 选取2023年3月～2025年3月医院收治的157例稳定期双相情感障碍患者为研究对象，分别采用世界卫生组织生活质量测定量表简表（World Health Organization Quality of Life Questionnaire, WHOQOL-BREF）、社会功能缺陷筛选量表（Social Disability Screening Schedule, SDSS）进行评估。Pearson法分析SDSS评分与生活质量的相关性，多元线性回归法分析生活质量的影响因素。

结果 患者生理、心理、社会关系、环境维度评分分别为（58.26±13.79）分、（49.34±8.53）分、（49.06±11.65）分、（51.42±12.31）分。患者生理维度评分在性别、年龄、心理弹性上有明显差异（P＜0.05），心理维度评分在病程、心理弹性上有明显差异（P＜0.05），社会关系维度评分在婚姻状态、心理弹性上有明显差异（P＜0.05），环境维度评分在年龄、心理弹性上有明显差异（P＜0.05）。合并社会功能缺陷组WHOQOL-BREF各维度评分均低于不合并社会功能缺陷组（P＜0.05）。SDSS评分与WHOQOL-BREF各维度评分呈明显正相关（P＜0.05）。性别（β=0.076）、社会功能（β=0.055）是影响生理维度的危险因素，心理弹性（β=0.025）是影响心理维度的危险因素，心理弹性（β=0.043、0.035）、社会功能（β=0.067、0.017）是影响社会关系、环境维度的危险因素（P＜0.05）。

结论 稳定期双相情感障碍患者生活质量有待提高，合并社会功能缺陷患者的生活质量水平较低；患者生活质量水平可能与性别、心理弹性及社会功能有关，应采取针对性干预措施，逐步改善患者生活质量。

关键词：【关键词】 双相情感障碍；稳定期；生活质量；社会功能；影响因素；相关性

ABSTRACT

[Abstract]
Objective To analyze the quality of life in patients with stable bipolar affective disorder and explore its correlation with social function.

Methods A total of 157 patients with stable bipolar affective disorder admitted to the hospital from March 2023 to March 2025 were selected as the study subjects, and were evaluated using the World Health Organization Quality of Life Questionnaire (WHOQOL-BREF) and the Social Disability Screening Schedule (SDSS). Their general clinical data were collected. Pearson’s method was used to analyze the correlation between SDSS score and quality of life. Multiple linear stepwise regression analysis was performed to screen factors influencing patients' quality of life.

Results The scores for physiological, psychological, social relationship and environmental dimensions of patients were (58.26±13.79), (49.34±8.53), (49.06±11.65) and (51.42±12.31), respectively. Scores in the physical domain differed significantly by gender, age, and resilience (P < 0.05); psychological domain scores by disease duration and resilience (P < 0.05); social relationships domain scores by marital status and resilience (P < 0.05); and environmental domain scores by age and resilience (P < 0.05). WHOQOL-BREF scores in various dimensions were lower in the group with social disability than in the group without social disability (P<0.05). There was a significant positive correlation between SDSS score and WHOQOL-BREF scores in various dimensions (P<0.05). The gender (β=0.076) and social function (β=0.055) were risk factors affecting physiological dimension. Psychological resilience (β=0.025) was a risk factor affecting psychological dimension. Psychological resilience (β=0.043, 0.035) and social function (β=0.067, 0.017) were risk factors affecting social relationship and environmental dimension (P<0.05).

Conclusion   The quality of life in patients with stable bipolar affective disorder needs to be improved, and it is relatively low in patients with social disability. The patients’ quality of life may be related to gender, psychological resilience, and social function. Therefore, targeted intervention measures should be taken to improve the quality of life.

Key words: [Key words] Bipolar affective disorder; Stable phase; Quality of life; Social function; Influencing factor; Correlation