本刊首页 > 期刊目次 > 七氟醚复合舒芬太尼全身麻醉在剖宫产术中的应用及对产妇血流动力学与新生儿氧摄取率的影响

• 文章 •

七氟醚复合舒芬太尼全身麻醉在剖宫产术中的应用及对产妇血流动力学与新生儿氧摄取率的影响

  • 孙应龙,林贤贵

* 通信作者: 林贤贵, 单位:重庆市大足区人民医院

摘要

[摘要]
目的 探讨七氟醚复合舒芬太尼全身麻醉在剖宫产术中的应用及对产妇血流动力学与新生儿氧摄取率的影响

方法 选择2016年2月至2018年2月我院接诊的92例实施剖宫产的产妇作为本研究对象,通过随机数表法分为观察组(n=46)和对照组(n=46),两组均以全身麻醉完成手术,对照组术中给予七氟醚进行麻醉诱导和麻醉维持,观察组联合舒芬太尼进行麻醉诱导和麻醉维持,比较两组围术期情况、不同时间点血流动力学、新生儿脐动脉血血气分析、Apgar评分和不良反应。

结果 两组手术时间、术中出血量、麻醉至胎儿娩出时间比较无显著差异(P>0.05);两组麻醉后5min(T1)、麻醉后10min(T2)、胎儿娩出时(T3)、术毕(T4)时点舒张压(SBP)、收缩压(DBP)、心率(HR)较入室时(T0)时点比较均显著降低(P<0.05),但观察组T1、T2、T3、T4时点SBP、DBP、HR均明显比对照组高(P<0.05);两组新生儿pH值比较无显著差异(P>0.05),但观察组新生儿氧分压(PO2)明显高于对照组,二氧化碳分压(PCO2)明显比对照组低[(63.34±2.03)mmHg vs(60.11±1.15)mmHg,(41.20±2.04)vs(44.72±2.28)mmHg](P<0.05);观察组1min、5min新生儿Apgar评分均明显比对照组高[(8.94±0.89)分vs(8.11±0.75)分,(9.89±0.07)分vs(9.78±0.05)分](P<0.05);观察组和对照组不良反应总发生率分别为15.22%(7/46)、10.87(5/46),比较无显著差异(P>0.05)。

结论 在剖宫产术中使用七氟醚复合舒芬太尼全身麻醉效果显著,其有助于保持产妇血流动力学稳定,且可增加新生儿氧摄取率,安全性高,值得应用推广。

关键词:【关键词】剖宫产;七氟醚;舒芬太尼;血流动力学;新生儿氧摄取率

ABSTRACT

[Abstract]
Objective To study the applicationof sevoflurane combined with sufentanil general anesthesia in treatment of cesarean section and effects on maternal hemodynamics and neonatal oxygen uptake rate.

Methods 92 patients of cesarean section who received therapy from February 2016 to February 2018 in our hospital were selected as research objects, according to random number table, those patients were divided into the observation group (n=46) and the control group (n=46). They were performed with general anesthesia. The control group was given sevoflurane anesthesia induction and anesthesia maintenance, while the observation group combined with sufentanil for anesthesia induction and anesthesia maintenance, the perioperative conditions, hemodynamics at different time points, umbilical artery blood gas analysis, Apgar scores and Adverse reaction were compared between the two groups.

Results There was no significant difference in operative time, intraoperative blood loss, and time of delivery from anesthesia to fetal delivery between the two groups(P>0.05); the diastolic pressure (SBP), systolic pressure (DBP) and heart rate (HR) after anesthesia 5min (T1), 10min (T2), fetal delivery (T3), and after operation (T4) of the two groups were significantly lower than those at the time of entry(T0)(P<0.05); but the SBP, DBP and HR at T1, T2, T3 and T4 in the observation group were significantly higher than those in the control group(P<0.05); there was no significant difference in pH between the two groups of newborns(P>0.05); but the neonatal oxygen partial pressure (PO2) in the observation group was significantly higher than those in the control group, and the partial pressure of carbon dioxide (PCO2) was significantly lower than those in the control group[(63.34±2.03)mmHg vs(60.11±1.15)mmHg,(41.20±2.04)vs(44.72±2.28)mmHg] (P<0.05); the 1min and 5min neonatal Apgar scores in the observation group were significantly higher than those in the control group[(8.94±0.89)scores vs(8.11±0.75)scores,(9.89±0.07)scores vs(9.78±0.05)scores](P<0.05); the total incidence of adverse reactions in the observation group and the control group were 15.22% (7/46) and 10.87 (5/46) respectively, and there was no significant difference(P>0.05).

Conclusion   Sevoflurane combined with sufentanil general anesthesia is well for cesarean section, which can help maintain maternal hemodynamic stability and increase neonatal oxygen uptake rate, it's safe and worthy of application.

Key words: Key words: Cesarean section; Sevoflurane; Sufentanil; Hemodynamics; Neonatal oxygen uptake rate

引用本文 / How to Cite This Article

孙应龙,林贤贵.七氟醚复合舒芬太尼全身麻醉在剖宫产术中的应用及对产妇血流动力学与新生儿氧摄取率的影响[J]. 国际精神病学杂志, , (): -

参考文献